The first major difference between the genera Brugmansia and Datura is that, while the angel's trumpet flowers of Brugmansia are pendulous, the Moonflowers or Datura point upwards. Secondly, Datura do not have a woody stem, are short-lived, herbaceous, perennial, and annual plants, while Brugmansia are woody to semi-woody and can live up to 20 years.